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Although by the age of 70, 80 percent of Caucasian men are male-like, scientists are still confused. Existing treatments were discovered by accident: The original treatment of high blood pressure was initially used, and the treatment of prostate hypertrophy was not enough. However, in a new study, researchers have discovered a molecule called prostaglandin D2 (PGD2), which inhibits the growth of male hair, which could provide a target for future drugs to treat baldness.
The first thing the researchers did was find a good use of scalp fragments, usually discarded, from men receiving hair transplants. (Well, where else can you find the scalding volunteers?) By comparing bald and non-vulture tissues in these scalp sites, they found that PGD2 in bald tissue was ten times higher than normal scalp, and that PTGDS (an enzyme that produces PGD2) was also higher than normal scalp. The PTGDS gene also expresses more when large amounts of testosterone float, which may explain why baldness is unique to men.
Once scientists determine that PGD2 is a potential cause of hair loss, the next step is to test it in mice. They found that the hair follicles of mutant mice with abnormally high PGD2 levels also atrophyed and their hair smaller. When the researchers placed PGD2 on the skin of live mice and on human follicles grown in petri dishes, they found that the molecule also inhibited hair growth there. The effect of PGD2 on male baldness?
Men who oppose baldness may find solace in the new treatment brought about by the discovery: PGD2 inhibits hair growth by requiring a receptor called GPR44, so eliminating it could mean saying goodbye to combed hair.
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The 17-year-old pop singer debuted her new look on Sunday, posting a selfie on Instagram showing off her neon green roots and brown hair, which were tied in two buns.
Although the musician's blue "do" has become her logo, she recently revealed that she is keen to dye it in a different color.
"The most annoying thing is: I hate blue - it's my least favorite color," Alesstold told Buzzfeed. "I don't know how I dyed it blue. I remember just living with it for a while, and then I realized I was a person with colored hair - I didn't record it. I have blue hair, but I don't think I'm a blue-haired person. I thought I had blue hair, that's me. Then I realized that when people walked past me, they might say, 'Oh, she's got blue hair. 'You know, it's like you see a man with colored hair. "
The star continued: 'I was told that whoever dyed my hair in October had a permanent blue so that s-t wouldn't come out. I sat in that stupid salon chair for hours, and time, and time, and time, and time, and time, and time, and time, and time, and time, and time, and hours, hours trying to come out blue b-h won't get my hair f-k out. "
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At the age of 32, I was diagnosed with the second stage of colon cancer. Since I have Crohn's disease, a chronic inflammatory bowel disease that increases the risk of colon cancer, I've been doing colonoscopies regularly. But in 2012, I began to experience some strange symptoms: I was diagnosed with anemia, I was losing weight, and I was generally tired. My colonoscopy has expired and I'll have one when I get back from a business trip. When I was traveling, I knew something was really wrong: I couldn't eat anything, and when I ate it, I felt the food get stuck.
Sure enough, my colonoscopy showed that I had colon cancer and needed immediate surgery.
The surgeon had my colon removed a lot and he wanted to put it in his pocket. I was terrified by the prospect - I was young and conceited, worried that it would affect my dating life. So, contrary to his better judgment, he gave me a j-shaped bag made from the patient's own small intestine to keep and excrete the feces. But this caused a lot of inflammation, which led me to go in and out of the hospital for several years (in fact, I spent more time in the hospital than I spent on chemotherapy and radiotherapy).
Four years ago, my j-bag was punctured in an emergency surgery, and everything was at a critical juncture. As a result, I had to have a recital," an operation to remove the end of the small intestine from the opening of the abdomen so that the faeces could leave my body. Unfortunately, this does require a pocket-making. I thought it was only temporary, but a few weeks later I realized that my quality of life had improved a lot. Previously, with a j-shaped nursery bag, I had serious anxiety about going to the car or eating because I often ran to the bathroom with diarrhea. I eat Imogen as candy. This is no longer a problem with my new pocket. I can go out to dinner or go to the movies with my friends without worrying about where the toilet is.
